Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | SEC14-like protein 2 |
Synonyms: | C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1, SEC14L2 |
Immunogen: | Recombinant protein corresponding to Mouse SEC14L2/TAP |
Uniprot ID: | Q99J08 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 45 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1500 | liver |
Background
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell (By similarity).
Images
Western blot analysis of SEC14L2 (GB114152) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |