Reactivity: | H,M,R & R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SERPING1 rabbit polyclonal antibody |
Gene Name: | Plasma protease C1 inhibitor |
Synonyms: | C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, Serping1, C1nh, HAE2, HAE1, complement component 1 inhibitor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SERPING1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 56 kDa |
Observed MW. | 100 kDa |
Uniprot ID: | P05155, P97290, Q6P734 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, heart |
IHC/IF | Rat | 1: 1000-1: 2000 | liver |
Background
C1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Images
Western blot analysis of C1INH (GB112165) at dilution of 1: 500 | |
Immunohistochemistry of paraffin embedded rat liver using C1INH (GB112165) at dilution of 1:1000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |