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Anti-SF3B1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SF3B1 rabbit polyclonal |
Gene Name: | Splicing factor 3B subunit 1 |
Synonyms: | PRP10, PRPF10, SAP-155, SAP155, SF3B1, SF3b155, Hsh 155, MDS, Pre mRNA processing 10, Spliceosome associated protein 155 |
Immunogen: | Recombinant protein corresponding to Mouse SF3B1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 146 kDa |
Observed MW. | 146 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 1000 | MCF-7, K562 |
Background
SF3B1, also named as SAP155, is a 1304 amino acid protein, which belongs to the SF3B1 family. SF3B1 is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. SF3B1 may also be involved in the assembly of the 'E' complex. SF3B1 belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Images
 | Western blot analysis of SF3B1 (GB113543) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
