Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SHANK2 rabbit polyclonal antibody |
Gene Name: | SH3 and multiple ankyrin repeat domains protein 2 |
Synonyms: | Shank2, Cortactin-binding protein 1, CortBP1, Kiaa1022, AUTS17, CTTNBP1, ProSAP1 |
Immunogen: | Recombinant protein corresponding to Mouse SHANK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | Q9QX74 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 300-1: 900 | cerebellum |
Background
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Images
Immunohistochemistry of paraffin embedded rat cerebellum using Shank2 (GB111985) at dilution of 1:300 (250x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |