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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SIRT3 rabbit polyclonal antibody |
Gene Name: | NAD-dependent protein deacetylase sirtuin-3 |
Synonyms: | SIRT3, SIR2L3, sirtuin 3, hSIRT3, SIR2 like protein 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SIRT3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28 kDa |
Observed MW. | 28 kDa |
Uniprot ID: | Q8R104 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 2000 | heart, kidney |
Background
NAD-dependent deacetylase sirtuin-3, mitochondrial also known as SIRT3 is member of the mammalian sirtuin family of proteins.NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Images
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Western blot analysis of Sirt3 (GB11354) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
