Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Excitatory amino acid transporter 4 |
Synonyms: | EAAT4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SLC1A6 |
Uniprot ID: | O35544 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 61 kDa / 70 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | testis, cerebral cortex |
Background
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable).
Images
Western blot analysis of SLC1A6 (GB114900) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |