Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Solute carrier family 22 member 2 |
Synonyms: | hOCT2, OCT2, Organic cation transporter 2, SLC22A2 |
Immunogen: | Recombinant protein corresponding to Mouse SLC22A2 |
Uniprot ID: | O70577 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 62 kDa / 60/80/100 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 600 | brain |
Background
Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX.
Images
Western blot analysis of SLC22A2 (GB114505) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |