Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Solute carrier family 22 member 6 |
Synonyms: | HOAT1, hPAHT, hROAT1, OAT1, Organic anion transporter 1, PAH transporter, PAHT, ROAT1, SLC22A6, Nkt, mROAT1, Novel kidney transcript |
Immunogen: | KLH conjugated Synthetic peptidecorresponding to Mouse SLC22A6 |
Uniprot ID: | Q8VC69 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 60 kDa / 80 kDa |
Product Usage Information
WB | Mouse | 1: 1000-1: 2000 | kidney |
IHC/IF | Mouse, Rat | 1: 2000-1: 4000 | kidney |
Background
OAT1, also named as SLC22A6, has two motifs in its transmembrane which is associated with protein processing and oligomerization of other proteins. OAT1 is involved in the renal elimination of endogenous and exogenous organic anions. It has been reported that OAT1 plays a key role in clearing endogenous metabolites, toxins and drugs from blood.
Images
Western blot analysis of SLC22A6 (GB113690) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using SLC22A6 (GB113690) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using SLC22A6 (GB113690) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |