Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Mitochondrial sodium/calcium exchanger protein/K(+)/Ca(2+)-exchange protein 6) |
Synonyms: | NCKX6, NCLX, SLC24A6, SLC8B1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human SLC24A6 |
Uniprot ID: | Q6J4K2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 64 kDa / 64 kDa |
Product Usage Information
WB | Human, Mouse | 1: 1000-1: 2000 | brain |
Background
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion . Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity). Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion,thereby affecting cytoplasmic calcium responses.
Images
Western blot analysis of SLC8B1 (GB115218) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |