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Anti-SLC25A33 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Solute carrier family 25 member 33 |
Synonyms: | BMSC MCP, HuBMSC MCP, Protein PNC1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SLC25A33 |
Uniprot ID: | Q3TZX3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 35 kDa / 36 kDa |
Product Usage Information
WB | Human | 1: 1500-1: 2000 | Hep G2, 293T, Molt-4 |
Background
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration. Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production.
Images
| Western blot analysis of SLC25A33 (GB115025) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
