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Anti-SMARCA2 / BRM Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SMARCA2 / BRM rabbit polyclonal antibody |
Gene Name: | Probable global transcription activator SNF2L2 |
Synonyms: | ATP-dependent helicase SMARCA2, BRG1-associated factor 190B, BAF190B, Protein brahma homolog, SNF2-alpha, Baf190b, Brm, Snf2a, Snf2l2, Smarca2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SMARCA2 / BRM |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 180 kDa |
Observed MW. | 250 kDa |
Uniprot ID: | P51531 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 350-1: 700 | HepG2, A-431, U-2OS |
Background
A transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 / BRM belongs to the SNF2/RAD54 helicase family, is a homologue of the Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma proteins. It contains a methyl lysine containing bromo domain and an HSA domain. The yeast protein SNF2, also known as SWI2, is involved in transcriptional activation of numerous genes. It contains a domain that is highly conserved among several known helicases and is required for transcriptional activity. SNF2/SWI2 is highly homologous to the Drosophila protein 'brahma' (brm).
Images
 | Western blot analysis of Brm (GB112508) at dilution of 1: 350 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
