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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SND1 rabbit polyclonal antibody |
Gene Name: | Staphylococcal nuclease domain-containing protein 1 |
Synonyms: | 100 kDa coactivator, p100 co-activator, SND1, TRD11, Tudor domain-containing protein 11, p100 EBNA2 co activator, p100 |
Immunogen: | Recombinant protein corresponding to Mouse SND1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 102 kDa |
Observed MW. | 102 kDa |
Uniprot ID: | Q7KZF4, Q78PY7, Q66X93 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | pancreas, liver |
Background
Staphylococcal nuclease domain-containing 1 (SND1), is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5, 6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC), and takes part in the functions of miRNA, regulates transcription through transcriptional coactivation, RNA interference, RNA splicing, and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer, can promote HCC angiogenesis in xenograft model through induction of angiogenic factors. This is a rabbit polyclonal antibody raised against near the C-terminus of human SND1.
Images
| Western blot analysis of SND1 (GB111902) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
