Reactivity: | H,M & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SNRNP200 rabbit polyclonal antibody |
Gene Name: | U5 small nuclear ribonucleoprotein 200 kDa helicase |
Synonyms: | BRR2 homolog, U5 snRNP-specific 200 kDa protein, U5-200KD, Snrnp200, Kiaa0788, BRR2, ASCC3L1, RP33 |
Immunogen: | Recombinant protein corresponding to Mouse SNRNP200 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 245 kDa |
Observed MW. | 245 kDa |
Uniprot ID: | O75643, Q6P4T2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | colon |
IHC/IF | Mouse, Rat | 1: 650-1: 1300 | ovary, testis |
Background
This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Images
Western blot analysis of SNRNP200 (GB112111) at dilution of 1: 500 | |
Immunofluorescence of paraffin embedded mouse testis using SNRNP200 (GB112111) at dilution of 1: 650 (250x lens) | |
Immunofluorescence of paraffin embedded rat ovary using SNRNP200 (GB112111) at dilution of 1: 650 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |