Your shopping cart is empty!
| Reactivity: | M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Sorting nexin-1 |
Synonyms: | HsT17379, SNX1, SNX1A, sorting nexin 1, Vps5 |
Immunogen: | Recombinant protein corresponding to Mouse SNX1 |
Uniprot ID: | Q9WV80 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Golgi apparatus, Endosome |
Predicted MW. / Observed MW. | 59 kDa / 71 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 800 | colon, uterine |
IHC/IF | Human | 1: 500-1: 1000 | breast cancer, gastric carcinoma |
Background
Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.
Images
| Western blot analysis of SNX1 (GB114554) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using SNX1 (GB114554) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human gastric carcinoma using SNX1 (GB114554) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human colon cancer using SNX1 (GB114554) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human liver cancer using SNX1 (GB114554) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
