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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SOX10 rabbit polyclonal antibody |
Gene Name: | Transcription factor SOX-10 |
Synonyms: | Sox10, SOX10, DOM, PCWH, WS2E, WS4, WS4C, SRY-box 10 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SOX10 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q04888, O55170 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 4000 | brain, heart, small intestine |
Background
Transcription factor SOX-10 encoded by the SOX10 gene is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. In melanocytic cells there is evidence that SOX10 gene expression may be regulated by MITF.
Images
 | Immunohistochemistry of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat heart using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse heart using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |