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Anti-SOX13 Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transcription factor SOX-13-box 13) |
Synonyms: | ICA12, Islet cell antigen 12, Sox 13, SOX13, Transcription factor SOX 13 |
Immunogen: | Recombinant protein corresponding to Mouse SOX13 |
Uniprot ID: | Q04891 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 68 kDa / 68 kDa |
Product Usage Information
WB | Rat | 1: 300-1: 800 | spinal cord |
Background
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor . Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Required for the differentiation of Vgamma2-positive gamma-delta T-cells, a subset of IL17A expressing gamma-delta T-cells . Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells . Promotes brown adipocyte differentiation. Inhibitor of WNT signaling (By similarity).
Images
| Western blot analysis of SOX13 (GB114391) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
