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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SPARC rabbit polyclonal antibody |
Gene Name: | SPARC |
Synonyms: | Basement membrane protein 40, Cysteine rich protein, Osteonectin, Secreted acidic cystein rich glycoprotein, Secreted protein acidic and rich in cysteine, Secreted protein acidic cysteine rich, BM 40, ON, OI17 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SPARC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 35 kDa |
Observed MW. | 40 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin, brain, testis |
Background
SPARC (Secreted protein acidic and rich in cysteine) also known as Osteonectin (ON) and basement-membrane protein 40 (BM-40), is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone mineral calcium. A correlation between osteonectin overexpression and ampullary cancers and chronic pancreatitis has been found.
Images
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Western blot analysis of Osteoncetin (GB11611) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
