Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SPRR3 rabbit polyclonal antibody |
Gene Name: | Small proline-rich protein 3 |
Synonyms: | Cornifin beta, Sprr3, Esophagin, SPRC, 22 kDa pancornulin |
Immunogen: | Recombinant protein corresponding to Mouse SPRR3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | O09116 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | esophagus |
Background
SPRR3, also named as Esophagin, Cornifin beta and SPRC, belongs to the cornifin (SPRR) family. It is cross-linked envelope protein of keratinocytes. Increased expression of SPRR3 appears to be involved in colorectal tumorigenesis. SPRR3 is a marker for terminal squamous cell differentiation.a potential novel therapeutic target for less advanced stages of Breast Cancer.
Images
Immunohistochemistry of paraffin embedded mouse esophagus using SPRR3 (GB111593) at dilution of 1:2000 (300x lens) |
|
Immunohistochemistry of paraffin embedded rat esophagus using SPRR3 (GB111593) at dilution of 1:2000 (300x lens) | |
Immunofluorescence of paraffin embedded mouse esophagus using SPRR3 (GB111593) at dilution of 1:2000 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |