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Anti-SQRDL Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Sulfide:quinone oxidoreductase, mitochondrial |
Synonyms: | SQOR, Sulfide quinone oxidoreductase, Sqor, Sqrdl, CGI44 |
Immunogen: | Recombinant protein corresponding to Mouse SQRDL |
Uniprot ID: | Q9R112 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 50 kDa / 50 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 4000 | kidney, liver, stomach |
ICC/IF | Human | 1: 100-1: 400 | Hela |
Background
SQRDL(Sulfide:quinone oxidoreductase, mitochondrial) catalyzes the oxidation of hydrogen sulfide, with the help of a quinone.Although the SQRDL precursor protein displays a molecular weight of 50 kDa,a prominent band at about 46 kDa is detected by western blot. This discrepancy reflects the cleavage of an N-terminal targeting sequence of 4 kDa during the import of the protein into the mitochondria(PMID:22067608).SQRDL is one of the enzymes involved in H2S signaling in a discrete population of neurons, oligodendrocytes, and endothelial cells.
Images
| Western blot analysis of SQRDL (GB112480) at dilution of 1: 2000 |
| Western blot analysis of SQRDL (GB112480) at dilution of 1: 2000 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using SQRDL(GB112480) at dilution of 1: 100-1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
