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Anti-Serum Response Factor SRF Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SRF rabbit polyclonal antibody |
Gene Name: | Serum response factor |
Synonyms: | c fos serum response element binding factor, SRF, ERP, MCM1, SAP2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse SRF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P11831, Q9JM73, D3ZHH8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | breast cancer, colon, heart, lung, lung cancer, ovarian cancer, prostate, small intestine, stomach, subcutaneous transplant tumor |
Background
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens and SRF) box super family of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using SRF (GB111048) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using SRF (GB111048) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded human ovarian cancer using SRF (GB111048) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded human stomach using SRF (GB111048) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded human subcutaneous transplant tumor using SRF (GB111048) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse heart using SRF (GB111048) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using SRF (GB111048) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using SRF (GB111048) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using SRF (GB111048) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded human prostate using SRF (GB111048) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse heart using SRF (GB111048) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse small intestine using SRF (GB111048) at dilution of 1:800 (400x lens) |
 | Immunofluorescence of paraffin embedded rat colon using SRF (GB111048) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using SRF (GB111048) at dilution of 1:800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
