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Anti-Serum Response Factor SRF Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Serum Response Factor SRF rabbit polyclonal antibody |
Gene Name: | Serum response factor |
Synonyms: | SRF, MCM1, serum response factor |
Immunogen: | Recombinant protein corresponding to Mouse Serum Response Factor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Hela, MCF7 |
Background
Serum response factor, also known as SRF, is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. SRF is important during the development of the embryo, as it has been linked to the formation of mesoderm. In the fully developed mammal, SRF is crucial for the growth of skeletal muscle. Interaction of SRF with other proteins, such as steroid hormone receptors, may contribute to regulation of muscle growth by steroids.
Images
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Western blot analysis of srf (GB11642) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
