Anti-SRGAP1 Rabbit pAb (100 μl)

Anti-SRGAP1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB113414-100
Availability: In Stock
$259.00
-+
Reactivity: H & H    
Applications: WB & IHC    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

SRGAP1 rabbit polyclonal

Gene Name:

SLIT-ROBO Rho GTPase-activating protein 1

Synonyms:

ARHGAP13, KIAA1304, SRGAP1, Rho GTPase-activating protein 13

Immunogen:

Recombinant protein corresponding to

Mouse SRGAP1

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Cytoplasm

Predicted MW.

121 kDa

Observed MW.

121 kDa

Uniprot ID:

Q7Z6B7




Product Usage Information

Applications

Species

Dilution

Positive tissue

WB

Human

1: 500-1: 1000

HepG2, Jurkat, 293T

IHC

Human

1: 300-1: 600

esophageal cancer, colon, placenta




Background

SRGAP1 (Slit-robo Rho GTPase activating protein 1), also known as ARHGAP13 (Rho GTPase activating protein 13), functions as a GTPase-activating protein for Cdc42 and Rho A. Expressed in kidney, testis, lung and brain, SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner.




Images

Western blot analysis of SRGAP1 (GB113414) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using SRGAP1 (GB113414) at dilution of 1: 600


Immunohistochemistry analysis of paraffin-embedded human colon using 

SRGAP1 (GB113414) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded human placenta using 

SRGAP1 (GB113414) at dilution of 1: 600




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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