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Anti-SRRM2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SRRM2 rabbit polyclonal antibody |
Gene Name: | Serine/arginine repetitive matrix protein 2 |
Synonyms: | Srrm2, Kiaa0324, CWC21, SRL300, TaxREB803, 300 kDa nuclear matrix antigen, SR-related nuclear matrix protein of 300 kDa, Splicing coactivator subunit SRm300 |
Immunogen: | Recombinant protein corresponding to Mouse SRRM2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8BTI8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 2000 | duodenum, skin, small intestine, uterus |
Background
The SRm160/300 splicing coactivator, which consists of the serine/arginine (SR)-related nuclear matrix protein and a nuclear matrix antigen, functions in splicing by promoting critical interactions between splicing factors bound to pre-mRNA. This splicing pathway involves five core small nuclear ribonucleoprotein particles (snRNPs) and the SR family proteins, which coordinately bind to pre-mRNA slicing enhancer elements, are required for accurate splice site recognition, and regulate alterative splicing patterns.
Images
| Immunohistochemistry of paraffin embedded mouse duodenum using SRRM2 (GB112043) at dilution of 1:650 (300x lens) |
| Immunohistochemistry of paraffin embedded mouse uterus using SRRM2 (GB112043) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse small intestine using SRRM2 (GB112043) at dilution of 1:650 (300x lens) |
| Immunofluorescence of paraffin embedded mouse skin using SRRM2 (GB112043) at dilution of 1:650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
