Reactivity: | M,R & H,M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SUCLG1 rabbit polyclonal |
Gene Name: | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial |
Synonyms: | Succinyl-CoA synthetase subunit alpha, SCS-alpha, Suclg1, SCS-alpha, GALPHA |
Immunogen: | Recombinant protein corresponding to Mouse SUCLG1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 36 kDa |
Observed MW. | 36 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 5000-1: 10000 | brain, cerebellum, stomach |
IHC | Human, Mouse, Rat | 1: 2000-1: 4000 | colon, stomach, small intestine, substantia nigra |
Background
SUCLG1(succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial) is also named as SCS-alpha and belongs to the succinate/malate CoA ligase alpha subunit family. The SUCLG1 gene encodes a 35 kDa protein with a 40 amino acids transit peptide. This enzyme catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. Defects in SUCLG1 are the cause of mitochondrial DNA depletion syndrome type 9 (MTDPS9).
Images
Western blot analysis of SUCLG1 (GB112774) at dilution of 1: 10000 Lane 1: NIH3T3 cell lysate Lane 2: Mouse brain tissue lysate Lane 3: Mouse cerebellum tissue lysate Lane 4: Mouse stomach tissue lysate Lane 5: Rat brain tissue lysate Lane 6: Rat cerebellum tissue lysate Lane 7: Rat stomach tissue lysate | |
Immunohistochemistry analysis of paraffin-embedded human colon using SUCLG1 (GB112774) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat colon using SUCLG1 (GB112774) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded human stomach using SUCLG1 (GB112774) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded mouse small intestine using SUCLG1 (GB112774) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat tsubstantia nigra using SUCLG1 (GB112774) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |