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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SV2A rabbit polyclonal antibody |
Gene Name: | Synaptic vesicle glycoprotein 2A |
Synonyms: | Synaptic vesicle protein 2, Synaptic vesicle protein 2A, Calcium regulator SV2A, Kiaa0736, Sv2 |
Immunogen: | Recombinant protein corresponding to Mouse SV2A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 83 kDa |
Observed MW. | 83 kDa |
Uniprot ID: | Q7L0J3, Q9JIS5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | kidney |
Background
SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimulated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters.
Images
 | Western blot analysis of SV2A (GB112189) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
