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Anti-Scavenging Receptor SR-BI Rabbit pAb (100 μl)
| Reactivity: | M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Scavenging Receptor SR-BI rabbit polyclonal antibody |
Gene Name: | Scavenger receptor class B member 1 |
Synonyms: | SRB1, SR-BI, Scarb1, CD36, CD36L1, Collagen type I receptor, CLA1 |
Immunogen: | Recombinant protein corresponding to Mouse Scavenging Receptor SR-BI |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 57 kDa |
Observed MW. | 80 kDa |
Uniprot ID: | Q61009 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 500-1: 1000 | testis |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 1200 | ovarian cancer, ovary |
Background
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells . Both isoform 1 and isoform 2 act as receptors for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux . Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity .
Images
| Western blot analysis of SRBI (GB112562) at dilution of 1: 500 |
| Immunofluorescence of paraffin embedded human ovarian cancer using SRBI (GB112562) at dilution of 1: 600 (250x lens) |
| Immunofluorescence of paraffin embedded mouse ovary using SRBI (GB112562) at dilution of 1: 600 (300x lens) |
| Immunofluorescence of paraffin embedded rat ovary using SRBI (GB112562) at dilution of 1: 600 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
