Reactivity: | M,R & H |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Selenium Binding Protein 1 / SBP rabbit polyclonal |
Gene Name: | Methanethiol oxidase |
Synonyms: | hSBP, hSP56, LPSB, SBP, SBP56, SELENBP1, selenium binding protein 1, SP56, Selenbp2, 56 kDa selenium-binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Selenium Binding Protein 1 / SBP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 53 kDa |
Observed MW. | 53 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 800 | liver, lung, colon |
IHC | Human | 1: 1200-1: 2400 | colon, kidney |
Background
SELENBP1 (selenium binding protein 1,SBP1), also known as LPSB or SP56, is a 472 amino acid peripheral membrane protein that binds selenium covalently. Selenium, an essential trace element, has been shown to have an anti-cancer effect. Many reports have described a relationship between insufficient selenium intake and increased risk of cancer. Moreover, the expression of SELENBP1 has been shown to be decreased in several tumors including cancers of the prostate, lungs, colon, and ovary . SELENBP1 has four isoforms with the molecular mass of 56kD, 52kD and 45kD.
Images
Western blot analysis of SBP (GB113279) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin-embedded human colon using SBP (GB113279) at dilution of 1: 2400 | |
Immunohistochemistry analysis of paraffin-embedded human kidney using SBP (GB113279) at dilution of 1: 2400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |