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Anti-Semaphorin 7a Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Semaphorin 7a rabbit polyclonal antibody |
Gene Name: | Semaphorin-7A |
Synonyms: | Semaphorin-K1, Sema K1, Semaphorin-L, Sema L, CD108, Sema7a, JMH, JMH blood group antigen |
Immunogen: | Recombinant protein corresponding to Mouse Semaphorin 7a |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 75 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | O75326, Q9QUR8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1500 | brain,testis |
Background
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Images
| Western blot analysis of Semaphorin-7A (GB111988) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
