Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Sialoadhesin/CD169 rabbit polyclonal antibody |
Gene Name: | Sialoadhesin |
Synonyms: | Sheep erythrocyte receptor, SER, Sialic acid-binding Ig-like lectin 1, Siglec-1, CD169, Siglec1, Sa, Sn, DKFZp667F058, CD169 antigen |
Immunogen: | Recombinantproteincorresponding to Mouse Sialoadhesin/CD169 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Uniprot ID: | Q9BZZ2, Q62230 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | lung, lymph node, spleen |
Background
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
Images
Immunohistochemistry of paraffin embedded mouse spleen using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spleen using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) | |
Immunofluorescence of paraffin embedded mouse lung using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) | |
Immunofluorescence of paraffin embedded rat lymph node using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) | |
Immunofluorescence of paraffin embedded rat spleen using Sialoadhesin (GB111685) at dilution of 1:700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |