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Anti-Slow Skeletal Myosin Heavy chain Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Slow Skeletal Myosin Heavy chain rabbit polyclonal |
Gene Name: | Myosin-7 |
Synonyms: | Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, MyHC-beta, CMD1S, CMH1, MPD1, MYH7, MyHC slow, MYHCB, Myosin 7, SPMD, SPMM |
Immunogen: | Recombinant protein corresponding to Mouse MYH7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 223 kDa |
Observed MW. | 223 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 250-1: 500 | heart, muscle |
| IHC/IF | Mouse, Rat | 1: 200-1: 400 | skeletal muscle |
Background
Myosin is the major contractile protein of all eukaryotic cells, existing as a hexameric molecule composed of two myosin heavy chains (MHCs) that contain the catalytic sites for ATP hydrolysis, and four lower molecular weight myosin light chains. MYH7 encodes the slow/beta-cardiac myosin heavy chain (MHC), which is the major MHC isoform of cardiac ventricles. It is also expressed in slow, oxidative, type 1 muscle fibers of skeletal muscle. Numerous mutations of MYH7 have been linked to familial hypertrophic cardiomyopathy.
Images
| Western blot analysis of MYH7 (GB111857) at dilution of 1: 500 Lane 1: Mouse heart tissue lysate Lane 2: Rat muscle tissue lysate |
| Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using MYH7 (GB111857) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using MYH7 (GB111857) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
