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Anti-Slow Skeletal Myosin Heavy chain Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Slow Skeletal Myosin Heavy chain rabbit polyclonal antibody |
Gene Name: | Myosin-7 |
Synonyms: | Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, MyHC-beta, MYH7, MYHCB, CMD1S, SPMM, SPMD, MPD1, Beta myosin heavy chain |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human MYH7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 223 kDa |
Observed MW. | 223 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 300-1: 600 | myocardium |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | leg muscle, muscle, skeletal muscle |
Background
This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading.
Images
| Western blot analysis of MYH7 (GB112131) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse leg muscle using MYH7 (GB112131) at dilution of 1: 100 |
| Immunohistochemistry analysis of paraffin-embedded rat leg muscle using MYH7 (GB112131) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat muscle using MYH7 (GB112131) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse skeletal muscle using MYH1 (GB112130, red ) and MYH7 (GB112131, green ) at dilution of 1: 100 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat skeletal muscle using MYH1 (GB112130, red ) and MYH7 (GB112131, green ) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat skeletal muscle using MYH1 (GB112130, red ) and MYH7 (GB112131, green ) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
