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Anti-Solute carrier family 22 member 5 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Solute carrier family 22 member 5 rabbit polyclonal antibody |
Gene Name: | Solute carrier family 22 member 5 |
Synonyms: | High-affinity sodium-dependent carnitine cotransporter, Organic cation/carnitine transporter 2, Slc22a5, Octn2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Slc22a5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q9Z0E8, O70594 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 900-1: 1800 | kidney |
Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.
Images
| Immunohistochemistry of paraffin embedded mouse kidney using SLC22A5 (GB112170) at dilution of 1:900 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using SLC22A5 (GB112170) at dilution of 1:900 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
