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Anti-Stanniocalcin 1/STC Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Stanniocalcin 1/STC rabbit polyclonal |
Gene Name: | Stanniocalcin-1 |
Synonyms: | STC, STC-1, STC1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Stanniocalcin 1/STC |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 800 | duodenum, kidney |
Background
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse duodenum using STC (GB113770) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded rat duodenum using STC (GB113770) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using STC (GB113770) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using STC (GB113770) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
