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Anti-SynCAM/CADM1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SynCAM/CADM1 rabbit polyclonal |
Gene Name: | Cell adhesion molecule 1 |
Synonyms: | BL2, CADM1, IGSF4, IGSF4A, Necl-2, NECL2, Nectin like protein 2, RA175, sgIGSF, ST17, sTSLC-1, SYNCAM, synCAM1, TSLC-1, TSLC1 |
Immunogen: | Recombinant protein corresponding to Mouse SynCAM/CADM1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 50 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2500 | testis, brain, lung |
Background
CADM1 (cell adhesion molecule 1), also referred to as SgIGSF, Necl-2 or TSLC-1, is a cell adhesion molecule belonging to the immunoglobulin superfamily. It can mediate homophilic and heterophilic cell-cell adhesion. CADM1 is expressed by a variety of cells including neurons, mast cells, spermatogonia, pancreatic islet cells, epithelial cells such as lung alveolar cells and biliary epithelial cells. CADM1 is involved in carcinoma pathogenesis and the expression of CADM1 is frequently down-regulated in various tumors derived from epithelial cells. It acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells.
Images
 | Western blot analysis of CADM1 (GB113445) at dilution of 1: 2500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
