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Anti-Synaptojanin Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Synaptojanin rabbit polyclonal |
Gene Name: | Synaptojanin-1 |
Synonyms: | INPP5G, KIAA0910, SYNJ1, Polyphosphoinositide phosphatase, PARK20, KIAA0910, 5-trisphosphate 5-phosphatase 1 |
Immunogen: | Recombinant protein corresponding to Mouse Synaptojanin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 173 kDa |
Observed MW. | 173 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 300-1: 800 | brain, stomach |
Background
Synaptojanin 1, a polyphosphoinositide phosphatase, is expressed as two major alternatively spliced isoforms of 145 kDa (SJ145) and 170 kDa (SJ170), which are thought to have pleiotropic roles in endocytosis, signaling and actin function. SJ145 is highly enriched in nerve terminals where it participates in clathrin-dependent synaptic vesicle recycling. SJ170, which differs from SJ145 by the presence of a carboxy-terminal extension, is the predominant isoform in developing neurons and is expressed in a variety of tissues.
Images
 | Western blot analysis of SYNJ1 (GB113172) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
