Reactivity: | M,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Synaptophysin |
Synonyms: | SYP, MRX96, MRXsynaptophysin, MRXSYP, Major Synaptic Vesicle Protein P38 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Synaptophysin |
Uniprot ID: | Q62277 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | synaptic vesicle membrane |
Predicted MW. / Observed MW. | 34 kDa / 38 kDa |
Images
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus |
Background
Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses.
Images
Western blot analysis of SYP (GB12553) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |