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Anti-Synphilin 1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Synphilin 1 rabbit polyclonal antibody |
Gene Name: | Synphilin-1 |
Synonyms: | Alpha-synuclein-interacting protein, Sncaip, Sph1, Synuclein alpha interacting protein |
Immunogen: | Recombinant protein corresponding to Mouse Synphilin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 106 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | Q99ME3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, brain, placenta |
IHC/IF | Mouse, Rat | 1: 400-1: 2000 | brain, heart |
Background
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.
Images
| Western blot analysis of Sncaip (GB111991) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse brain using Sncaip (GB111991) at dilution of 1: 650 (300x lens) |
 | Immunohistochemistry of paraffin embedded mouse heart using Sncaip (GB111991) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using Sncaip (GB111991) at dilution of 1: 400 (200x lens) |
| Immunohistochemistry of paraffin embedded rat heart using Sncaip (GB111991) at dilution of 1: 650 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
