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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TAF4 rabbit polyclonal antibody |
Gene Name: | TATA-box-binding protein-associated factor 4 |
Synonyms: | Taf4, Taf4a, TAF2C, TAFII 130, TAFII 135, TBP associated factor 4, TAF4b RNA polymerase II, TAFII 105, RNA polymerase II, C2 |
Immunogen: | Recombinantproteincorresponding to Mouse TAF4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | E9QAP7 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 450-1: 1300 | duodenum |
Background
TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA).
Images
| Immunohistochemistry of paraffin embedded mouse duodenum using TAF4 (GB111725) at dilution of 1:450 (400x lens) |
| Immunohistochemistry of paraffin embedded rat duodenum using TAF4 (GB111725) at dilution of 1:450 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
