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Anti-TIP-1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tax1-binding protein 3 |
Synonyms: | Tax interaction protein 1, Tax1 binding protein 3, TAX1BP3, TIP 1, TIP1 |
Immunogen: | Recombinant protein corresponding to Mouse TIP-1 |
Uniprot ID: | Q9DBG9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus, Cell membrane |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | lung cancer, brian |
Background
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway.
Images
| Immunohistochemistry analysis of paraffin embedded human lung cancer using TAX1BP3 (GB115386) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse brian using TAX1BP3 (GB115386) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat brian using TAX1BP3 (GB115386) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
