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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TLR2 rabbit polyclonal |
Gene Name: | Toll-like receptor 2 |
Synonyms: | TLR2, CD282, TIL4, Toll like receptor, Toll/interleukin 1 receptor like protein 4, Toll like receptor 2 precursor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TLR2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | Q9QUN7 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 3000 | inflammatory spleen |
IF | Mouse, Rat | 1: 500-1: 1000 | inflammatory spleen |
Background
Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282 (cluster of differentiation 282). TLR2 is one of the toll-like receptors and plays a role in the immune system. TLR2 is a membrane protein, a receptor, which is expressed on the surface of certain cells and recognizes foreign substances and passes on appropriate signals to the cells of the immune system. In the intestine, TLR2 regulates the expression of CYP1A1, which is a key enzyme in detoxication of carcinogenic polycyclic aromatic hydrocarbons such as benzo(a)pyrene.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse inflammatory spleen using TLR2 (GB11554) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat inflammatory spleen using TLR2 (GB11554) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
