Anti-TMP21 Rabbit pAb (100 μl)

Anti-TMP21 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB113721-100
Availability: In Stock
$259.00
-+
Reactivity: M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

TMP21 rabbit polyclonal

Gene Name:

Transmembrane emp24 domain-containing protein 10

Synonyms:

P24(DELTA), p24delta, S31I125, S31III125, TMED10, Tmp 21 I, TMP21, Transmembrane protein Tmp21, 21 kDa transmembrane-trafficking protein, TMP21

Immunogen:

KLH conjugated Synthetic peptide

corresponding to Mouse TMP21

Isotype:

IgG

Purity:

Affinity purification

Predicted MW.

25 kDa

Observed MW.

21 kDa

Uniprot ID:

Q9D1D4, Q63584




Product Usage Information

Applications

Species

Dilution

Positive tissue

WB

Mouse, Rat

1: 1000-1: 2000

liver, lung 




Background

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.




Images

Western blot analysis of TMP21 (GB113721) 

at dilution of 1: 2000




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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