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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TN-X rabbit polyclonal |
Gene Name: | Tenascin X |
Synonyms: | Hexabrachion like protein, HXBL, Tenascin X, tenascin XB, TENX, TN X, TNX, TNXB, TNXB1, TNXB2, TNXBS, XB, XBS |
Immunogen: | Recombinant protein corresponding to Mouse TN-X |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 435 kDa |
Observed MW. | 75 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 800 | brain, lung |
Background
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM) . It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This antibody is raised against human TNXB and detects a band about 75 kDa, which probably represent a proteolytic cleaved form of human TNXB.
Images
 | Western blot analysis of TN-X (GB113388) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
