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Anti-TNF Receptor I Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tumor necrosis factor receptor superfamily member 1A |
Synonyms: | CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TNF R1 |
Uniprot ID: | P25118 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Golgi apparatus |
Predicted MW. / Observed MW. | 50 kDa / 50-55 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 400 | brain |
Background
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
Images
| Western blot analysis of TNF Receptor I (GB115567) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
