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Anti-TNFAIP3 Rabbit pAb (100 μl)
| Reactivity: | H & H,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tumor necrosis factor alpha-induced protein 3 |
Synonyms: | TNF alpha-induced protein 3, Putative DNA-binding protein A20, Zinc finger protein A20, Tnfaip3, Tnfip3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TNFAIP3 |
Uniprot ID: | Q60769 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Lysosome, Nucleus |
Predicted MW. / Observed MW. | 88 kDa / 88 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | 293T, HepG2, A-431 |
IHC/IF | Human, Rat | 1: 650-1: 1300 | lung cancer, lung, lymph gland |
Background
TNFAIP3, also named A20, is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NFKB) activity and tumor necrosis factor (TNF)-mediated programmed cell death. A20 is a ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities, and involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity.
Images
| Western blot analysis of TNAP3 (GB112182) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraffin embedded human colon cancer using TNAP3 (GB112182) at dilution of 1: 650 |
| Immunofluorescent analysis of paraffin embedded rat lung using TNAP3 (GB112182) at dilution of 1: 650 |
| Immunofluorescent analysis of paraffin embedded rat lymph gland using TNAP3 (GB112182) at dilution of 1: 650 |
| Immunofluorescent analysis of paraffin embedded rat lung using TNAP3 (GB112182) at dilution of 1: 650 |
 | Immunofluorescent analysis of paraffin embedded human lung cancer using TNAP3 (GB112182) at dilution of 1: 650 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
