Your shopping cart is empty!
Anti-TRAFD1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | TRAF-type zinc finger domain-containing protein 1 |
Synonyms: | FLN29, Protein FLN29, TRAFD1 |
Immunogen: | Recombinant protein corresponding to Mouse TRAFD1 |
Uniprot ID: | Q3UDK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 3000 | testis |
Background
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
Images
| Immunohistochemistry analysis of paraffin embedded rat testis using TRAFD1 (GB114698) at dilution of 1: 1000 |
| Immunofluorescence of paraffin embedded mouse testis using TRAFD1 (GB114698) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
