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Anti-TRAM2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Translocating chain-associated membrane protein 2 |
Synonyms: | KIAA0057, TRAM2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TRAM2 |
Uniprot ID: | Q924Z5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 43 kDa / 40 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 4000 | heart |
Background
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Images
| Western blot analysis of TRAM2 (GB114627) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
