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Anti-TRAP80 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TRAP80 rabbit polyclonal antibody |
Gene Name: | Mediator of RNA polymerase II transcription subunit 17 |
Synonyms: | Cofactor required for Sp1 transcriptional activation subunit 6, CRSP complex subunit 6, CRSP complex subunit 6, Med17, Trap80, Crsp6 |
Immunogen: | Recombinant protein corresponding to Mouse TRAP80 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8VCD5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | brain, testis |
Background
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.
Images
| Immunohistochemistry of paraffin embedded rat brain using MED17 (GB111723) at dilution of 1:1500 (200x lens) |
| Immunohistochemistry of paraffin embedded rat testis using MED17 (GB111723) at dilution of 1:1500 (200x lens) |
| Immunofluorescence of paraffin embedded rat brain using MED17 (GB111723) at dilution of 1:1500 (200x lens) |
 | Immunofluorescence of paraffin embedded rat testis using MED17 (GB111723) at dilution of 1:600 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
