Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | E3 ubiquitin-protein ligase TRIM62 |
Synonyms: | FLJ10759; FLJ16558 |
Immunogen: | Recombinant protein corresponding to Mouse TRIM62 |
Uniprot ID: | Q80V85 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 54 kDa / 50 kDa |
Product Usage Information
WB | Mouse | 1: 800-1: 1500 | brain |
Background
E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways.E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
Images
WB analysis of TRIM62(GB115615). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |