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Anti-TTK/Mps1 Rabbit pAb (100 μl)
| Reactivity: | M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Dual specificity protein kinase TTK |
Synonyms: | ESK, MPS1, MPS1L1, PYT, TTK, TTK protein kinase |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Mouse TTK |
Uniprot ID: | P35761 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 96 kDa / 100 kDa |
Product Usage Information
WB | Mouse | 1: 300-1: 500 | testis |
Background
Phosphorylates proteins on serine, threonine, and tyrosine (By similarity). Probably associated with cell proliferation (By similarity). Phosphorylates MAD1L1 to promote mitotic checkpoint signaling (By similarity). Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint (By similarity).
Images
| Western blot analysis of TTK (GB115460) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
