Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Tumor suppressor candidate 3 |
Synonyms: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3, ligosaccharyl transferase subunit TUSC3, Magnesium uptake/transporter TUSC3, Protein N33, Tusc3, N33 |
Immunogen: | Recombinant protein corresponding to Mouse TUSC3 |
Uniprot ID: | Q8BTV1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 40 kDa / 40 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, spinal cord, pituitary gland |
Background
TUSC3 (tumor suppressor candidate 3), originally named N33, is a potential tumor supressor gene. Decreased expression of TUSC3 has been found in various cancers, including prostate cancer, pancreas cancer and ovary cancer. TUSC3 also known as OST3A, is identified as a part of the oligosaccharyl-transferase (OST) complex and plays a crucial role in protein N-glycosylation. TUSC3 mutations have been found in families with non-syndromic autosomal recessive mental retardation.
Images
Western blot analysis of TUSC3 (GB111821) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |